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Flu Network Studies

Flu network vaccine effectiveness studies

Several studies comprise this area of research.  The CDC’s US Flu VE Network study is a 5-site national study that provides influenza vaccine effectiveness estimates against medically attended influenza in outpatient sites.  Data from this study contribute to the WHO strain selection for the influenza vaccine for the Northern Hemisphere and to CDC influenza vaccine policy decisions. 

The CDC’s Hospitalized Adult Influenza Vaccine Effectiveness Network (HAIVEN) similarly assesses influenza vaccine effectiveness estimates against hospitalization in 4 sites across the US.  It also looks at the hospitalized burden of RSV and influenza.

A new study funded by Sanofi, will use data from electronic medical records to compare acute respiratory-related health care utilization between recipients of egg-based and cell-based influenza vaccine types.

COVID-19 studies

As an offshoot of the two CDC-funded influenza vaccine effectiveness studies, inpatient and outpatient cases of COVID-19 are being studied to understand epidemiology, symptoms and sequelae of the infection.   Preprint available at

RSV studies

The epidemiology, burden, and cost of respiratory syncytial virus (RSV) infection in adults is being studied using state-level and UPMC Health System-level data.